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AFN-1252 [CAS 620175-39-5]

AFN-1252 [CAS 620175-39-5]

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SKU:QM-0154234-01

£200.66 GBP
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  • Description

    AFN-1252 is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC90 values of ⩽0.015 μg/ml against diverse clinical isolates of S. aureus. AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith[1][2].

  • CAS Number

    [620175-39-5]

  • Molecular Formula

    C22H21N3O3

  • Molecular Weight

    375.42

  • Smiles

    O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C(C=C3CC4)=CNC3=NC4=O

  • Target

    Antibiotic; Bacterial

  • Purity

    99.49

  • Solubility

    DMSO : 5.8 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0154234-01
5 mgQM-0154234-01
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10 mM - 1 mLQM-0154234-02
10 mM - 1 mLQM-0154234-02
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10 mgQM-0154234-03
10 mgQM-0154234-03
£288.14/ea
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£288.14/ea £0.00
50 mgQM-0154234-04
50 mgQM-0154234-04
£803.30/ea
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AFN-1252 [CAS 620175-39-5]

AFN-1252 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.