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Afuresertib [CAS 1047644-62-1]

Afuresertib [CAS 1047644-62-1]

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SKU:QM-0152245-01

£70.54 GBP
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  • Description

    Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively[1][2].

  • CAS Number

    [1047644-62-1]

  • Molecular Formula

    C18H17Cl2FN4OS

  • Molecular Weight

    427.32

  • Smiles

    O=C(C1=CC(C2=C(Cl)C=NN2C)=C(Cl)S1)N[C@@H](CC3=CC=CC(F)=C3)CN

  • Target

    Akt; PKC; ROCK

  • Isoform

    Akt1; Akt2; Akt3; PKCβ; PKCη; PKCθ; ROCK

  • Concentration

    10mM

  • Purity

    99.53

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C (Powder, protect from light, stored under nitrogen)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
1 mgQM-0152245-01
1 mgQM-0152245-01
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5 mgQM-0152245-02
5 mgQM-0152245-02
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10 mM - 1 mLQM-0152245-03
10 mM - 1 mLQM-0152245-03
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10 mgQM-0152245-04
10 mgQM-0152245-04
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50 mgQM-0152245-05
50 mgQM-0152245-05
£497.12/ea
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100 mgQM-0152245-06
100 mgQM-0152245-06
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Afuresertib [CAS 1047644-62-1]

Afuresertib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.