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SKU:QM-0152245-01
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Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively[1][2].
[1047644-62-1]
C18H17Cl2FN4OS
427.32
O=C(C1=CC(C2=C(Cl)C=NN2C)=C(Cl)S1)N[C@@H](CC3=CC=CC(F)=C3)CN
Akt; PKC; ROCK
Akt1; Akt2; Akt3; PKCβ; PKCη; PKCθ; ROCK
10mM
99.53
DMSO : 100 mg/mL (ultrasonic)
-20°C (Powder, protect from light, stored under nitrogen)
Blue Ice
H302, H315, H319, H335
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Afuresertib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.