AGN 191976 [CAS 159359-94-1]

AGN 191976 is a potent and selective thromboxane A2-sensitive (TP) receptor agonist with EC50 values ​​of 0.23 nM and 24 nM in rat aorta and human platelets, respectively. AGN 191976 has potent IOP-lowering effects in dogs and monkeys. AGN 191976 can be used to study vascular biology and the role of thromboxane A2 in vascular function[1].

[159359-94-1]

C21H32O6

380.48

O=C(CCC/C=C\C[C@H]1[C@]2(OC(O[C@@]([H])([C@@H]1/C=C/[C@H](CCCCC)O)C2)=O)[H])O

Prostaglandin Receptor

Room temperature