Name: AKN-028 (acetate)
Brand: QuantiMol
SKU: QM-0139373-01
Price: 140.88 GBP
Availability: InStock

Product Details

Description
AKN-028 acetate, a novel tyrosine kinase (TK) inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. AKN-028 acetate inhibits FLT3 autophosphorylation. AKN-028 acetate induces dose-dependent cytotoxic response (mean IC50=1 μM) . AKN-028 acetate induces apoptosisby activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia (AML) .
Molecular Formula
C19H18N6O2
Molecular Weight
362.39
Smiles
NC1=NC=C(N=C1NC2=CC3=C(C=C2)NC=C3)C4=CC=NC=C4.CC(O)=O
Target
Apoptosis; Caspase; FLT3
Purity
98.38
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Shipping Conditions
Room Temperature

Your cart
Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0139373-01	5 mgQM-0139373-01 £140.88/ea	£0.00	Quantity	£140.88/ea	£0.00

10 mM - 1 mLQM-0139373-02	10 mM - 1 mLQM-0139373-02 £188.51/ea	£0.00	Quantity	£188.51/ea	£0.00

10 mgQM-0139373-03	10 mgQM-0139373-03 £263.84/ea	£0.00	Quantity	£263.84/ea	£0.00

25 mgQM-0139373-04	25 mgQM-0139373-04 £489.83/ea	£0.00	Quantity	£489.83/ea	£0.00

50 mgQM-0139373-05	50 mgQM-0139373-05 £740.12/ea	£0.00	Quantity	£740.12/ea	£0.00

100 mgQM-0139373-06	100 mgQM-0139373-06 £1,241.91/ea	£0.00	Quantity	£1,241.91/ea	£0.00

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AKN-028 (acetate)

AKN-028 (acetate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.