AL-34662 (formate) is a 5-HT2 receptor agonist (IC50: 0.8-1.5 nM) . AL-34662 (formate) stimulates inositol phosphate turnover and Ca2+ release in human ciliary muscle cells (h-CM) (E50: 289 nM) and human trabecular meshwork cells (h-TM) (E50: 254 nM) . AL-34662 (formate) can be used in studies to lower intraocular pressure (IOP) [1].
