Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 [CAS 211190-38-4]
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 [CAS 211190-38-4]
SKU:QM-0085365
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Product Details
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Description
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'[1].
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CAS Number
[211190-38-4]
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Molecular Formula
C42H63FN12O8
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Molecular Weight
883.02
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Smiles
O=C(N[C@@H](CC1=CC=C(F)C=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2CCCCC2)C(N[C@@H](CCCNC(N)=O)C(N[C@@H](CC3=CC=C(C=C3)O)C(N)=O)=O)=O)=O)=O)[C@H](C)N
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Target
Protease Activated Receptor (PAR)
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Isoform
PAR1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 [CAS 211190-38-4]
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.