ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with an IC50 of 1.61 μM. ALDH3A1-IN-1 is more potent than DEAB against patient-derived primary prostate tumor epithelial cells, as single agents or in combination research with docetaxel[1].
CAS Number
[1039855-56-5]
Molecular Formula
C13H18N2O3
Molecular Weight
250.29
Smiles
O=CC1=CC([N+]([O-])=O)=C(C=C1)N(CCC)CCC
Target
Aldehyde Dehydrogenase (ALDH)
Isoform
ALDH3
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)