ALK5-IN-27 [CAS 2785430-83-1]

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SKU:QM-0069280

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Description
ALK5-IN-27 (Compound EX-04) is a potent ALK-5 inhibitor with an IC50 ≤10 nM. ALK5-IN-27 also inhibits ALK-2 (selectivity ALK2/ALK5 ≤10) [1].
CAS Number
[2785430-83-1]
Molecular Formula
C25H28N8
Molecular Weight
440.54
Smiles
CN1CCN(CC2=CC(NC3=NC=CC(NC4=C5C=CC=C(C)C5=NN=C4)=N3)=CC=C2)CC1
Target
TGF-β Receptor
Isoform
ALK2; ALK5
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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ALK5-IN-27 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.