Name: ALK5-IN-8 [CAS 2705900-81-6]
Brand: QuantiMol
SKU: QM-0148139-01
Price: 426.65 GBP
Availability: InStock

Product Details

Description
ALK5-IN-8 is a potent inhibitor of TGFβRI (ALK5) . ALK5-IN-8 Inhibits the phosphorylation of ALK5 on its downstream signaling proteins (Smad2 or Smad3) by blocking the binding of TGFβRI to ligands, thereby affecting or blocking TGF-β signaling. ALK5-IN-8 has the potential for the research of various ALK5-mediated related diseases (extracted from patent WO2021190425A1, compound 1) [1].
CAS Number
[2705900-81-6]
Molecular Formula
C19H15FN4O2
Molecular Weight
350.35
Smiles
O=C(C1=C2C=C(C3=CNN=C3C4=CC=C(F)C=C4)C=CN2N=C1)OCC
Target
TGF-β Receptor
Concentration
10mM
Purity
98.21
Solubility
DMSO : 50 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0148139-01	5 mgQM-0148139-01 £426.65/ea	£0.00	Quantity	£426.65/ea	£0.00

10 mM - 1 mLQM-0148139-02	10 mM - 1 mLQM-0148139-02 £464.31/ea	£0.00	Quantity	£464.31/ea	£0.00

10 mgQM-0148139-03	10 mgQM-0148139-03 £614.98/ea	£0.00	Quantity	£614.98/ea	£0.00

25 mgQM-0148139-04	25 mgQM-0148139-04 £1,241.91/ea	£0.00	Quantity	£1,241.91/ea	£0.00

50 mgQM-0148139-05	50 mgQM-0148139-05 £1,933.25/ea	£0.00	Quantity	£1,933.25/ea	£0.00

100 mgQM-0148139-06	100 mgQM-0148139-06 £3,061.99/ea	£0.00	Quantity	£3,061.99/ea	£0.00

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ALK5-IN-8 [CAS 2705900-81-6]

ALK5-IN-8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.