Alkyne-P60

Alkyne-P60 is a potent 15-mer peptide inhibitor of Foxp3. Alkyne-P60 can bind with Foxp3, hinder its nuclear translocation, and diminish Foxp3-mediated inhibition of NFKB and NFAT functions. Alkyne-P60 is a ligand for target protein for PROTAC.

C101H139N25O20S2

2087.47

O=C(CCCC#C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCSC)=O)C)=O)CC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)=O)CC4=CNC5=C4C=CC=C5)=O)CCSC)=O)CCCCN)=O)=O)CC6=CC=CC=C6)=O)=O)CCC(N)=O)=O)CC7=CC=CC=C7)=O)CC(O)=O)=O)CCCNC(N)=N

Ligands for Target Protein for PROTAC

99.96

DMSO : 100 mg/mL (ultrasonic)

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice