ALR2-IN-8

ALR2-IN-8 is a potent aldose reductase (ALR2/AKR1B1) inhibitor with a KI of 7.34 nM. ALR2-IN-8 has extremely low toxicity to normal cells and has a weak direct killing effect on cancer cells. ALR2-IN-8 can used for the studies of diabetic and inflammation-linked disorders[1].

C19H11Br4NO6

668.91

O=C(OCC(OCC)=O)C1=CC=C(N(C(C2=C3C(Br)=C(Br)C(Br)=C2Br)=O)C3=O)C=C1

Aldose Reductase

Room temperature