Amb123203 [CAS 956571-77-0]

Amb123203 is an antiviral compound with the activity of inhibiting viral budding. Amb123203 exerts its effect by blocking the interaction between mVP40 and Nedd4 proteins. Amb123203 has a significant inhibitory effect on the budding of VP40 virus-like particles (VLPs) of Marburg (MARV) and Ebola viruses. Amb123203 can effectively target RNA viruses that rely on the PPxY L domain for efficient budding, showing broad-spectrum antiviral activity. The discovery of Amb123203 provides an important basis for the development of new broad-spectrum antiviral compounds[1].

[956571-77-0]

C25H27N5OS

445.58

O=C(CN1CCCC(C1)C2=NC3=C(S2)C=CC=C3)NC4=C(C)N(C5=CC=CC=C5)N=C4C

Endogenous Metabolite

98.87

DMSO : ≥ 100 mg/mL

-20°C, 3 years (Powder)

Blue Ice

H302, H315, H319, H335

H302, H315, H319, H335