Amezinium (methylsulfate) [CAS 30578-37-1]
Amezinium (methylsulfate) [CAS 30578-37-1]
SKU:QM-0157342-01
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Product Details
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Description
Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake. Target: alpha and beta-1 receptors Amezinium metilsulfate is a sympathomimetic drug used for the treatment of low blood pressure. Cardiovascular effects of the new sympathomimetic Amezinium metilsulphate are investigated in 25 patients compared with a control group (n = 25) . During spinal/epidural anaesthesia 5 mg amezinium is given i.v. if blood pressure dropped greater than 20 mmHg. from starting-point. A significant recovery of blood pressure (epidural anaesthesia: syst 21%, diast 9%; spinal anaesthesia: syst 13%, diast 6.6%) and a decrease in heart rate (6.8% resp. 4,5%) are thought due to peripheral vasoconstriction. Amezinium proves a stimulating drug for alpha- and beta 1-receptors by stabilising the systemic blood pressure in spinal/epidural anaesthesia.
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CAS Number
[30578-37-1]
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Molecular Formula
C12H15N3O5S
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Molecular Weight
313.33
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Smiles
COC1=CC(N)=CN=[N+]1C2=CC=CC=C2.O=S(OC)([O-])=O
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Target
Adrenergic Receptor
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Purity
99.72
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Solubility
DMSO : ≥ 34 mg/mL|H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Amezinium (methylsulfate) [CAS 30578-37-1]
Amezinium (methylsulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.