Amg-1 [CAS 496023-55-3]

Amg-1 is a potent, reversible and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor (IC50 = 3.0 μM) . Amg-1 exhibits >80-fold selectivity over IDO2 (IC50 > 250 μM) and >20-fold selective over TDO (IC50 > 62.5 μM) . Amg-1 can be used for cancer, hypotension, and neurological disorders research[1].

[496023-55-3]

C20H16N4O3S2

424.5

O=C(NC1=CC=C(OCO2)C2=C1)CSC3=NN=C4N3C(C5=CC=C(C)C=C5)=CS4

Indoleamine 2,3-Dioxygenase (IDO)

IDO1; IDO2

99.9

-20°C, 3 years (Powder)

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