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SKU:QM-0139888-01
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AMG-208 is an orally active c-Met/RON dual selective inhibitor with an IC50 of 9 nM for c-Met. AMG-208 is a CYP3A4 inhibitor with an IC50 of 32 μM. AMG-208 has anti-cancer activity[1][2][3].
[1002304-34-8]
C22H17N5O2
383.4
COC1=CC=C2C(OCC3=NN=C4N3N=C(C=C4)C5=CC=CC=C5)=CC=NC2=C1
C-Met/HGFR; Cytochrome P450
CYP3; Met
99.86
DMSO : 3.33 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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AMG-208 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.