AMG-221 [CAS 1095565-81-3]

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SKU:QM-0083892-01

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Product Details

Description
AMG-221 is an inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with a Ki of 12.8 nM in vitro biochemical scintillation proximity assay (SPA) and an IC50 of 10.1 nM in cell-based assays[1][2]. AMG-221 can be used for the research of type 2 diabetes[3].
CAS Number
[1095565-81-3]
Molecular Formula
C14H22N2OS
Molecular Weight
266.4
Smiles
O=C1N=C(N[C@@H]2[C@@](C3)([H])CC[C@@]3([H])C2)S[C@@]1(C)C(C)C
Target
11β-HSD
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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10 mgQM-0083892-01	10 mgQM-0083892-01 £0.00/ea	£0.00	Quantity	£0.00/ea	£0.00

110 mgQM-0083892-02	110 mgQM-0083892-02 £0.00/ea	£0.00	Quantity	£0.00/ea	£0.00

50 mgQM-0083892-03	50 mgQM-0083892-03 £0.00/ea	£0.00	Quantity	£0.00/ea	£0.00

5 mgQM-0083892-04	5 mgQM-0083892-04 £0.00/ea	£0.00	Quantity	£0.00/ea	£0.00

100 mgQM-0083892-05	100 mgQM-0083892-05 £0.00/ea	£0.00	Quantity	£0.00/ea	£0.00

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AMG-221 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.