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SKU:QM-0151052-01
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AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively[1].
[473719-41-4]
C32H28F3N5O4
603.59
O=C(N([C@@H](C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(OC(F)(F)F)C=C5
CXCR
CXCR3
99.8
DMSO : ≥ 41 mg/mL
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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AMG 487 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.