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AMG 487 [CAS 473719-41-4]

AMG 487 [CAS 473719-41-4]

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SKU:QM-0151052-01

£231.03 GBP
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  • Description

    AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively[1].

  • CAS Number

    [473719-41-4]

  • Molecular Formula

    C32H28F3N5O4

  • Molecular Weight

    603.59

  • Smiles

    O=C(N([C@@H](C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(OC(F)(F)F)C=C5

  • Target

    CXCR

  • Isoform

    CXCR3

  • Purity

    99.8

  • Solubility

    DMSO : ≥ 41 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0151052-01
5 mgQM-0151052-01
£231.03/ea
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10 mM - 1 mLQM-0151052-02
10 mM - 1 mLQM-0151052-02
£289.36/ea
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10 mgQM-0151052-03
10 mgQM-0151052-03
£306.37/ea
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£306.37/ea £0.00
50 mgQM-0151052-04
50 mgQM-0151052-04
£614.98/ea
£0.00
£614.98/ea £0.00
100 mgQM-0151052-05
100 mgQM-0151052-05
£991.63/ea
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£991.63/ea £0.00

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AMG 487 [CAS 473719-41-4]

AMG 487 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.