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AMG PERK 44 [CAS 1883548-84-2]
AMG PERK 44 [CAS 1883548-84-2]
SKU:QM-0141989-01
£238.32 GBP
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Product Details
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Description
AMG PERK 44 is an orally active and highly selective PERK inhibitor with an IC50 of 6 nM. AMG PERK 44 has 1000-fold and 160-fold selectivity over GCN2 (IC50=7300 nM) and B-Raf (IC50 >1000 nM), respectively. AMG PERK 44 induces autophagy[1][2].
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CAS Number
[1883548-84-2]
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Molecular Formula
C34H29ClN4O2
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Molecular Weight
561.07
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Smiles
O=C1N(C2=CC=CC=C2)N(C)C(C3=CC=CC=C3)=C1C(C4=CC=C(C)C(C5=CC=C6N=C(C)C=CC6=C5)=C4N)=O.[H]Cl
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Target
Autophagy; PERK
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Concentration
10mM
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Purity
99.67
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Solubility
DMSO : 25 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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AMG PERK 44 [CAS 1883548-84-2]
AMG PERK 44 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.