Amilo-5MER (TFA)

Amilo-5MER (5-MP) TFA is an orally active and selective Serum Amyloid A (SAA) inhibitor. Amilo-5MER TFA specifically inhibits the release of pro-inflammatory cytokines IL-6 and IL-1β from SAA-activated cells. Amilo-5MER TFA reduces chronic inflammation and relieves symptoms of diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and multiple sclerosis (MS) . Amilo-5MER TFA is promising for research of autoimmune diseases and chronic inflammatory diseases[1].

C23H40N6O9S.xC2HF3O2

CC(C)[C@@H](C(N)=O)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H]([C@H](O)C)NC([C@@H](NC(C)=O)CCSC)=O)=O)=O)=O.O=C(C(F)(F)F)O.[x]

Amyloid-β; Interleukin Related

99.63

0.1 M Acetic acid : 0.5 mg/mL (ultrasonic) |DMSO : 25 mg/mL (ultrasonic)

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice