(+) -Amosulalol [CAS 94666-17-8]

(+) -Amosulalol ((+) -YM 09538) is an isomer of Amosulalol , an orally active dual inhibitor of α1/β1-adrenergic receptors. Amosulalol exhibits antihypertensive activity by inhibiting α1-adrenergic receptors. Amosulalol reduces the reflex increase in heart rate and plasma renin activity (PRA) in spontaneously hypertensive rats (SHR) by inhibiting β1-adrenergic receptors.

[94666-17-8]

C18H24N2O5S

380.46

O=S(C1=CC([C@H](O)CNCCOC2=CC=CC=C2OC)=CC=C1C)(N)=O

Adrenergic Receptor

Room temperature