Ampyrone [CAS 83-07-8]
Ampyrone [CAS 83-07-8]
SKU:QM-0159749-01
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Product Details
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Description
Ampyrone (4-Aminophenazone; 4-Aminoantipyrine) is a reversible and low-damage optical clearing agent and non-selective COX inhibitor based on UV absorption properties. Ampyrone can improve the optical transmittance of mouse skin and other tissues. Ampyrone can induce tissue refractive index matching by enhancing UV absorption, reduce light scattering, and achieve tissue transparency in vivo. Ampyrone reduces the synthesis of prostaglandin PGE2, thereby exerting anti-inflammatory, analgesic and antipyretic effects. Ampyrone inhibits DNA damage, cell apoptosis and immune cell phagocytosis induced by Doxorubicin and Cisplatin (HY-17394), etc., and participates in the regulation of toxicity in tumor chemotherapy[1][2][3].
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CAS Number
[83-07-8]
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Molecular Formula
C11H13N3O
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Molecular Weight
203.25
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Smiles
O=C1N(C2=CC=CC=C2)N(C)C(C)=C1N
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Target
COX; Drug Metabolite
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Isoform
COX
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Purity
99.72
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Solubility
DMSO : ≥ 50 mg/mL|H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Ampyrone [CAS 83-07-8]
Ampyrone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.