Ampyrone-d3 [CAS 1329792-51-9]
Ampyrone-d3 [CAS 1329792-51-9]
SKU:QM-0159750-01
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Product Details
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Description
Ampyrone-d3 is the deuterium labeled Ampyrone. Ampyrone (4-Aminophenazone; 4-Aminoantipyrine) is a reversible and low-damage optical clearing agent and non-selective COX inhibitor based on UV absorption properties. Ampyrone can improve the optical transmittance of mouse skin and other tissues. Ampyrone can induce tissue refractive index matching by enhancing UV absorption, reduce light scattering, and achieve tissue transparency in vivo. Ampyrone reduces the synthesis of prostaglandin PGE2, thereby exerting anti-inflammatory, analgesic and antipyretic effects. Ampyrone inhibits DNA damage, cell apoptosis and immune cell phagocytosis induced by Doxorubicin (HY-15142A) and Cisplatin (HY-17394), etc., and participates in the regulation of toxicity in tumor chemotherapy[1][2][3].
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CAS Number
[1329792-51-9]
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Molecular Formula
C11H10D3N3O
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Molecular Weight
206.26
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Smiles
O=C1N(C2=CC=CC=C2)N(C(C)=C1N)C([2H])([2H])[2H]
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Target
COX; Drug Metabolite; Isotope-Labeled Compounds
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Ampyrone-d3 [CAS 1329792-51-9]
Ampyrone-d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.