Amylin (8-37), human [CAS 135702-23-7]

Amylin (8-37), human is a fragment of human Amylin. Amylin (8-37), human has direct vasodilator effects in the isolated mesenteric resistance artery of the rat. Human Amylin is a small hormone secreted by pancreatic β-cells that forms aggregates under insulin deficiency metabolic conditions, and it constitutes a pathological hallmark of type II diabetes mellitus[1].

[135702-23-7]

C138H216N42O45

3183.5

OC(C=C1)=CC=C1C[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(N)=O)NC([C@H](CO)NC(CNC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CO)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](C)NC(CNC([C@H](CC2=CC=CC=C2)NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H](CO)NC([C@H](CC3=CN=CN3)NC([C@H](C(C)C)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H]([C@H](O)C)NC([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Amylin Receptor

10 mM in DMSO

Room temperature