AN11251 [CAS 2130750-59-1]

AN11251 is a potent and oral active anti-Wolbachia agent with potential for treatment of onchocerciasis and lymphatic filariasis, with EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines[1].

[2130750-59-1]

C29H38BFO7

528.42

O=C(O[C@H]1[C@@]([C@H](C)CC2)(C)[C@@](C(CC3)=O)([H])[C@]32[C@@H](C)[C@H](O)[C@](C)(C=C)C1)COC4=CC=C5COB(O)C5=C4F

Parasite

10 mM in DMSO

Room temperature