AN11736 [CAS 2152662-85-4]

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SKU:QM-0003773

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Description
AN11736 is a CPSF3 inhibitor. AN11736 exerts a potent anti-trypsin effect by specifically inhibiting the activity of the trypanosome CPSF3 endonuclease, disrupting the mRNA maturation process. AN11736 exhibits IC50s against T. congolense and T. vivax of 0.14 and 1.3 nM, respectively. AN11736 exhibits strong anti-trypsin activity in mouse and cattle models[1][2].
CAS Number
[2152662-85-4]
Molecular Formula
C21H23BFNO5
Molecular Weight
399.22
Smiles
OB1OCC2=CC=C(C(N[C@@H](C(C)C)C(OCC3=CC=C(F)C=C3)=O)=O)C(C)=C21
Target
MRNA; Parasite
Shipping Conditions
Room temperature

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AN11736 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.