Anagliptin-d7

Anagliptin-d7 (SK-0403-d7) is deuterium labeled Anagliptin. Anagliptin (SK-0403) is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC50 of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC50s of 68 nM and 60 nM, respectively[1].

C19H18D7N7O2

390.49

O=C(NCC(NCC(N1[C@](C([2H])([2H])C([2H])([2H])C1([2H])[2H])([2H])C#N)=O)(C)C)C2=CN3C(N=C2)=CC(C)=N3

Dipeptidyl Peptidase; Isotope-Labeled Compounds

Room temperature