ANKFY1 is a proposed Rab5 effector that critically participates in endosomal dynamics by binding to PI (3) P, promoting homotypic early endosomal fusion and participating in heterotypic fusion. It plays a crucial role in macropinocytosis, is dependent on Rab5-GTP, and is essential for the correct localization of activated tyrosine kinase receptors such as PDGFRB. ANKFY1 Protein, Human (sf9, His, Strep) is the recombinant human-derived ANKFY1 protein, expressed by sf9 insect cells , with N-Strep, N-8*His labeled tag.
