ANO1-IN-5

ANO1-IN-5 is an orally active ANO1 inhibitor with an IC50 of 4.57 μM. J ANO1-IN-5 demonstrates 118-, 642-, and 10000-fold selectivity over α1A-, α1B-, andα1D-AR, respectively. ANO1-IN-5 exhibits significant inhibitory effects on osteoclast differentiation and function. ANO1-IN-5 can used for the study of osteoporosis[1].

C23H33N3O4S

447.59

O=S(C1=CC(CC(NC2CCN(C3=CC=CC=C3OCC)CC2)C)=CC=C1OC)(N)=O

Chloride Channel

Room temperature