Antibacterial agent 110 [CAS 9007-83-4]

Antibacterial agent 110 (Compound 4e) is a potent antibacterial agent with a MIC value of 1 μg/mL against P. aeruginosa. Antibacterial agent 110 possesses favorable antibiofilm activity and can destroy cell membranes. Antibacterial agent 110 causes metabolic arrest and intracellular oxidative stress, and obstructs DNA replication[1].

[9007-83-4]

C22H21N5O4S

451.5

CN1C=CN=C1SCC(CN2C(/C(C3=C2C=CC=C3)=N\NC4=CC=C(C=C4)C(O)=O)=O)O

Bacterial; DNA/RNA Synthesis; ROS Kinase

10 mM in DMSO

Room temperature