Antibacterial agent 182 [CAS 9007-83-4]

Antibacterial agent 182 (compound 8c) is an antibacterial agent that shows antibacterial activity against various Gram-positive bacteria, particularly against Vancomycin-resistant Enterococcus faecalis (MIC ≤0.125 μg/mL) . Antibacterial agent 182 inhibits biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa at sub-MIC doses[1].

[9007-83-4]

C14H5Br4F3N2OS

625.88

BrC(N1)=C(Br)C(Br)=C1C2=NC(C3=C(O)C(Br)=CC(C(F)(F)F)=C3)=CS2

Bacterial

10 mM in DMSO

Room temperature