Antibacterial agent 231 [CAS 9007-83-4]

Antibacterial agent 231 (derivative 8) is an antimicrobial agent against multidrug-resistant Helicobacter pylori (H. pylori) with a minimum inhibitory concentration of 0.25–0.5 μg/mL. Antibacterial agent 231 directly targets the protein transposase subunit SecA and the outer membrane protein assembly factor BamD to inhibit the trafficking and assembly of bacterial outer membrane proteins (OMPs) . Antibacterial agent 231 can be used to study the effects of antibiotic treatment on intestinal microbial balance[1].

[9007-83-4]

C28H32BrNO4

526.46

COC1=C(OC/C=C/C)C=C2C(C(C(C/C=C/C)=C(C=CC(OC)=C3OC)C3=C4)=[N+]4CC2)=C1.[Br-]

Bacterial

Room temperature