Antileishmanial agent-16 [CAS 2934738-41-5]

Antileishmanial agent-16 (compound 14c) is an anti-Leishmania agent. Antileishmanial agent-16 has superior anti-Leishmania major promastigotes activity (IC50 = 0.59 µM) and anti-Leishmania major amastigotes activity (IC50 = 0.81 µM) . Antileishmanial agent-16 has good safety to mammalian cells (VERO cells) [1].

[2934738-41-5]

C27H37N5O4

495.61

CCCCOC1=CC2=C(C=C(C(O2)=O)C(NCCCCCCN3C=C(N=N3)CN4CCCC4)=O)C=C1

Parasite

10 mM in DMSO

Room temperature