Antimalarial agent 11 [CAS 1214454-56-4]

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SKU:QM-0067086

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Description
Antimalarial agent 11 (compound 1), a spirocyclic chromane, is a potent antimalarial agent. Antimalarial agent 11 exhibits excellent potency with an EC50 of 350 nM against the Chloroquine-resistant Dd2 strain. Antimalarial agent 11 has EC50s of 1.48 µM and 1.81 µM against D6 and ARC08-022 strains, respectively[1].
CAS Number
[1214454-56-4]
Molecular Formula
C25H25F2NO3
Molecular Weight
425.47
Smiles
OC(CN1CCC2(CC(O)C3=C(O2)C4=C(C=CC=C4)C=C3)CC1)C5=CC=C(F)C(F)=C5
Target
Parasite
Isoform
Plasmodium
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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Antimalarial agent 11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.