Antimicrobial agent-1 [CAS 2579696-45-8]

Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 μg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128 μg/mL in Caco-2 and Vero cell lines[1].

[2579696-45-8]

C22H21N3O2S

391.49

CS(=O)(NC1=CC=CC(C2=NC3=CC=CC=C3N2CC4=CC=C(C)C=C4)=C1)=O

Bacterial

10 mM in DMSO

Room temperature