Antituberculosis agent-5 (compound 52) is a nitrofuranylamide derivative, inhibits M. tuberculosis UDP-Gal mutase. Antituberculosis agent-5 inhibits Glf activity with an IC50 value of 99 μM/mL and resists tuberculosis (TB) with a MIC value of 1.6 μg/mL[1].
CAS Number
[313981-44-1]
Molecular Formula
C13H12N2O5
Molecular Weight
276.24
Smiles
O=C(C1=CC=C([N+]([O-])=O)O1)NCC2=CC=CC=C2OC
Target
Bacterial
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)