Anxiolytic/nonsedative agent-1 [CAS 355022-97-8]
Anxiolytic/nonsedative agent-1 [CAS 355022-97-8]
SKU:QM-0057375
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Product Details
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Description
Anxiolytic/nonsedative agent-1 (compound 2b) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo[1].
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CAS Number
[355022-97-8]
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Molecular Formula
C18H15N3O4
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Molecular Weight
337.33
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Smiles
O=C(N[C@@H](C1=CC=CC=C1)C)C(C2=CNC3=C2C=C([N+]([O-])=O)C=C3)=O
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Target
GABA Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319
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Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
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Anxiolytic/nonsedative agent-1 [CAS 355022-97-8]
Anxiolytic/nonsedative agent-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.