AP-6 [CAS 1369963-51-8]

AP-6 is a selective inhibitor of TMEM175 with activity in modulating lysosomal function. Acute inhibition of TMEM175 by AP-6 increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. AP-6 may be used in Parkinson's disease research[1].

[1369963-51-8]

C16H14N4

262.31

NC1=CC(C2=CC=CC(C3=CC(N)=CC=N3)=C2)=NC=C1

Potassium Channel

99.84

DMSO : 0.93 mg/mL (ultrasonic; warming; adjust pH to 3 with 1 M HCL; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature