AP-C5 displays selective inhibition of guanosine 3′,5′-cyclic monophosphate (cGMP) -dependent protein kinase II (cGKII) with a pIC50 of 7.2, which can be used for the research of diarrheal disease[1]. AP-C5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[2234272-10-5]
Molecular Formula
C16H13N5
Molecular Weight
275.31
Smiles
C#CCNC1=NC=CC(C2=CC=C(N3C=CN=C3)C=C2)=N1
Target
Biochemical Assay Reagents
Purity
98.14
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)