APN-PEG36-tetrazine

APN-PEG36-tetrazine is an analogue of APN-PEG4-tetrazine. APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. APN-PEG36-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

C94H161N7O38

1997.3

N#CC#CC1=CC=C(C(NCCOCCOCCC(NCC2=CC=C(C3=NN=CN=N3)C=C2)=O)=O)C=C1.[35]

ADC Linker

96.05

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C (Powder, protect from light, stored under nitrogen)

Blue Ice