Apoptolidin [CAS 194874-06-1]
Apoptolidin [CAS 194874-06-1]
SKU:QM-0060906
Couldn't load pickup availability
Request quote or documents
![Apoptolidin [CAS 194874-06-1]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
Apoptolidin is a polyketide isolated from Nocardiopsis bacteria[1]. Apoptolidin is a selective mitochondrial F1FO ATPase inhibitor. Apoptolidin is an apoptosis inducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA (IC50=10-17 ng/ml) but not in normal cells[1][2].
-
CAS Number
[194874-06-1]
-
Molecular Formula
C58H96O21
-
Molecular Weight
1129.37
-
Smiles
O[C@H]([C@](OC(/C(C)=C/C(C)=C/C(C)=C/[C@H]1C)=O)([H])C[C@@H]([C@H](CC/C=C(/C=C/[C@H]1O[C@H](O[C@H]2C)[C@H]([C@@H]([C@H]2OC)O)O)C)O)OC)[C@](O[C@@H]([C@@H]3C)C[C@H](COC)O[C@H](O[C@H]4C)C[C@](O)([C@H]4O[C@H](O[C@@H]5C)C[C@H]([C@@H]5O)OC)C)([C@@H]([C@H]3O)C)O
-
Target
Apoptosis; ATP Synthase
-
Purity
95.6
-
Solubility
DMSO : 1 mg/mL (ultrasonic; warming)
-
Storage Conditions
-20°C, 3 years (Powder)
-
Shipping Conditions
Blue Ice
-
Hazard Statement
H302, H315, H319, H335
-
Precautions
H302, H315, H319, H335
Related Products
Other industry favorites
Apoptolidin [CAS 194874-06-1]
Apoptolidin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.