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APX-115 (free base) [CAS 1270084-92-8]

APX-115 (free base) [CAS 1270084-92-8]

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SKU:QM-0140042-01

£200.66 GBP
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  • Description

    APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base effectively prevents kidney injury[1].

  • CAS Number

    [1270084-92-8]

  • Molecular Formula

    C17H17N3O

  • Molecular Weight

    279.34

  • Smiles

    OC1=C(CCC)C(C2=CC=CC=C2)=NN1C3=NC=CC=C3

  • Target

    NADPH Oxidase

  • Isoform

    NOX1; NOX2; NOX4

  • Purity

    99.54

  • Solubility

    DMSO : 250 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0140042-01
5 mgQM-0140042-01
£200.66/ea
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10 mM - 1 mLQM-0140042-02
10 mM - 1 mLQM-0140042-02
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10 mgQM-0140042-03
10 mgQM-0140042-03
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25 mgQM-0140042-04
25 mgQM-0140042-04
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£577.31/ea £0.00
50 mgQM-0140042-05
50 mgQM-0140042-05
£902.93/ea
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100 mgQM-0140042-06
100 mgQM-0140042-06
£1,430.24/ea
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APX-115 (free base) [CAS 1270084-92-8]

APX-115 (free base) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.