APX879 [CAS 1801372-27-9]

APX879 is a fungal-specific calcineurin inhibitor that has less immunosuppressive activities and toxicities. APX879 is a C22-modified FK506 analog, which maintains broad-spectrum antifungal activity[1][2].

[1801372-27-9]

C46H73N3O12

860.08

CO[C@@H]1[C@]2([H])O[C@]([C@@H](C1)C)(C(C(N3[C@](CCCC3)([H])C(O[C@@H]([C@@H]([C@H](C/C([C@@H](/C=C(C[C@@H](C[C@@H]2OC)C)\C)CC=C)=N/NC(C)=O)O)C)/C(C)=C/[C@H]4C[C@H]([C@@H](CC4)O)OC)=O)=O)=O)O

Calcineurin; Fungal

95.36

4°C (Powder, protect from light, stored under nitrogen)

Room Temperature