Arg-Glu (edans) -Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys (dabcyl) -Arg

Arg-Glu (edans) -Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys (dabcyl) -Ar is a fluorogenic renin substrate based on the N-terminal tetradecapeptide sequence of human angiotensinogen (hTDP) [1].

C129H179N37O24S

2664.1

O=C(N[C@@H](CCC(NCCNC1=CC=CC2=C1C=CC=C2S(=O)(O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC3=CNC=N3)C(N4[C@@H](CCC4)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC6=CNC=N6)C(N7[C@@H](CCC7)C(N[C@@H](CC8=CC=CC=C8)C(N[C@@H](CC9=CNC=N9)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC%10=CNC=N%10)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCNC(C%11=CC=C(C=C%11)/N=N/C%12=CC=C(C=C%12)N(C)C)=O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N

Angiotensin Receptor

10 mM in DMSO

Room temperature