ARN14494 [CAS 1037837-27-6]

Name: ARN14494 [CAS 1037837-27-6]
Brand: QuantiMol
SKU: QM-0138654-01
Price: 702.46 GBP
Availability: InStock

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SKU:QM-0138654-01

£702.46 GBP

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Product Details

Description
ARN14494 is a potent and selective serine palmitoyltransferase (SPT) inhibitor, with an IC50 of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from β-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti-apoptosis, and anti-inflammation. ARN14494 can be used for Alzheimer’s disease research[1].
CAS Number
[1037837-27-6]
Molecular Formula
C24H32N4O3
Molecular Weight
424.54
Smiles
O=C(C1=CC2=C(N(C3CCN(CC(N4CC5C(CCC5)C4)=O)CC3)C(C2)=O)C=C1)NC
Target
Apoptosis; COX; Interleukin Related; NO Synthase
Isoform
COX-2; IL-1; iNOS
Purity
99.08
Solubility
10 mM in DMSO
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0138654-01	5 mgQM-0138654-01 £702.46/ea	£0.00	Quantity	£702.46/ea	£0.00

10 mgQM-0138654-02	10 mgQM-0138654-02 £1,136.21/ea	£0.00	Quantity	£1,136.21/ea	£0.00

25 mgQM-0138654-03	25 mgQM-0138654-03 £2,328.13/ea	£0.00	Quantity	£2,328.13/ea	£0.00

50 mgQM-0138654-04	50 mgQM-0138654-04 £3,697.43/ea	£0.00	Quantity	£3,697.43/ea	£0.00

100 mgQM-0138654-05	100 mgQM-0138654-05 £5,886.86/ea	£0.00	Quantity	£5,886.86/ea	£0.00

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ARN14494 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.