Name: ARN1468 [CAS 1381459-14-8]
Brand: QuantiMol
SKU: QM-0150328-01
Price: 376.83 GBP
Availability: InStock

Product Details

Description
ARN1468 (compound 5) is an orally active and potent SerpinA3n inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC50 values of 8.64, 19.3, 11.2, and 6.27 μM[1].
CAS Number
[1381459-14-8]
Molecular Formula
C16H17F3N4O2
Molecular Weight
354.33
Smiles
O=C(C1=C(N(C2=CC=C(OC(F)(F)F)C=C2)N=C1)N)C3CCNCC3
Target
Prion Protein
Purity
98.96
Solubility
DMSO : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0150328-01	5 mgQM-0150328-01 £376.83/ea	£0.00	Quantity	£376.83/ea	£0.00

10 mM - 1 mLQM-0150328-02	10 mM - 1 mLQM-0150328-02 £408.43/ea	£0.00	Quantity	£408.43/ea	£0.00

10 mgQM-0150328-03	10 mgQM-0150328-03 £527.50/ea	£0.00	Quantity	£527.50/ea	£0.00

25 mgQM-0150328-04	25 mgQM-0150328-04 £1,053.59/ea	£0.00	Quantity	£1,053.59/ea	£0.00

50 mgQM-0150328-05	50 mgQM-0150328-05 £1,656.23/ea	£0.00	Quantity	£1,656.23/ea	£0.00

100 mgQM-0150328-06	100 mgQM-0150328-06 £2,685.34/ea	£0.00	Quantity	£2,685.34/ea	£0.00

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ARN1468 [CAS 1381459-14-8]

ARN1468 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.