AS19 [CAS 1000578-26-6]

AS19 is a potent, selective 5-HT7 receptor agonist with an IC50 value of 0.83 nM and a Ki of 0.6 nM. AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis = 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively) . AS19 enhances memory consolidation and reverses Scopolamine- or Dizocilpine-induced amnesia[1][2][3].

[1000578-26-6]

C18H25N3

283.41

CC1=C(C2=CC=CC3=C2CC[C@H](N(C)C)C3)C(C)=NN1C

5-HT Receptor

5-HT1 Receptor;5-HT5 Receptor;5-HT7 Receptor; mLAG-3; MUC3; Prostaglandin D Synthase

99.69

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years (Powder)

Blue Ice

H302, H315, H319, H335

H302, H315, H319, H335