ASIP/Agouti proteins tightly regulate melanogenesis by binding to the melanocortin-1 receptor (MC1R), disrupting alpha-melanocyte stimulating hormone (α-MSH) signaling, and inhibiting cyclic AMP (cAMP) production. This down-regulates eumelanin production, shifting pigmentation toward a yellow/red color. ASIP/Agouti Protein, Human (His, Myc) is the recombinant human-derived ASIP/Agouti, expressed by E. coli Cell-free, with C-Myc, N-10*His labeled tag. The total length of ASIP/Agouti Protein, Human (His, Myc) is 110 a.a..
Molecular Formula
434 (Gene_ID) P42127 (H23-C132) (Accession)
Purity
90
Storage Conditions
Stored at -20°C for 2 years
Shipping Conditions
Room temperature in continental US; may vary elsewhere.