Aspartylglutamate (Asp-Glu) is a dipeptide that exhibits excitatory activity, as it has been shown to depolarize CA1 pyramidal neurons and increase conductance in response to stimulation. Aspartylglutamate selectively binds to certain glutamate receptors and demonstrates potent effects in specific regions of the hippocampus, particularly in the stratum radiatum where it enhances excitatory neurotransmission.
CAS Number
[6157-06-8]
Molecular Formula
C9H14N2O7
Molecular Weight
262.22
Smiles
OC(C[C@H](N)C(N[C@H](C(O)=O)CCC(O)=O)=O)=O
Target
Endogenous Metabolite
Purity
99.79
Solubility
DMSO : 12 mg/mL (ultrasonic; warming; heat to 60°C)