Atazanavir (sulfate) [CAS 229975-97-7]
Atazanavir (sulfate) [CAS 229975-97-7]
SKU:QM-0154444-01
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Product Details
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Description
Atazanavir (BMS-232632) sulfate is a highly selective and orally active HIV-1 protease inhibitor . Atazanavir sulfate is a substrate and inhibitor of CYP3A4, and an inhibitor of P-glycoprotein (P-gp) . Atazanavir sulfate is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. Atazanavir sulfate inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death[1][2][3][4][5][6][7][8].
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CAS Number
[229975-97-7]
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Molecular Formula
C38H54N6O11S
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Molecular Weight
802.93
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Smiles
O=C(OC)N[C@@H](C(C)(C)C)C(NN(CC1=CC=C(C2=NC=CC=C2)C=C1)C[C@H](O)[C@H](CC3=CC=CC=C3)NC([C@H](C(C)(C)C)NC(OC)=O)=O)=O.O=S(O)(O)=O
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Target
Cytochrome P450; Endogenous Metabolite; HIV; HIV Protease; P-glycoprotein; SARS-CoV; Toll-like Receptor (TLR)
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Isoform
CYP3; HIV-1
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Purity
99.68
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Solubility
DMSO : 166 mg/mL (ultrasonic; warming) |H2O : < 0.1 mg/mL
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H318, H372
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Precautions
H318, H372
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Atazanavir (sulfate) [CAS 229975-97-7]
Atazanavir (sulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.