ATR kinase substrate peptide
ATR kinase substrate peptide
SKU:QM-0200006-01
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Product Details
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Description
ATR kinase substrate peptide (compound 45) is a potent and selective inhibitor of ATR (Ataxia Telangiectasia and Rad3 related) protein kinase (Ki=6 nM) . ATR kinase substrate peptide inhibits ATR activity by competing with ATR kinase ATP-binding sites to block ATR mediated signaling. ATR kinase substrate peptide can be used to study the role of ATR kinase in DNA damage response[1].
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Molecular Formula
C81H132N22O25
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Molecular Weight
1814.05
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Smiles
O=C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N2[C@@H](CCC2)C(N[C@@H](CCC(N)=O)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N
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Target
ATM/ATR
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Isoform
ATR
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Purity
99.17
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Solubility
H2O : 28 mg/mL (ultrasonic; warming)
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Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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ATR kinase substrate peptide
ATR kinase substrate peptide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.